Novel steroidal inhibitors of human cytochrome P45017. alpha.-hydroxylase-C17, 20-lyase): potential agents for the treatment of prostatic cancer

GA Potter, SE Barrie, M Jarman…

Index: Journal of Medicinal Chemistry, , vol. 38, # 13 p. 2463 - 2471

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Citation Number: 295

Abstract

... 000 will die of metastatic prostatic cancer.l The most widely ac- cepted drug treatment is the use of GnRH agonists, which act by interfering with the production of test- osterone by the testes and represent a medical alterna- tive ... 2466 Journal of Medicinal Chemistry, 1995, Vol. ...