Preparative bioorganic chemistry, XV. Preparation of optically pure 2, 4, 4??trimethyl??2??cyclohexen??1??ol, a new and versatile chiral building block in terpene synthesis

K Mori, P Puapoomchareon

Index: Mori, Kenji; Puapoomchareon, Prapai Liebigs Annalen der Chemie, 1991 , # 10 p. 1053 - 1056

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Citation Number: 23

Abstract

Department of Agricultural Chemistry, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113, Japan ... Key Words: Asymmetric hydrolysis / Chiral alcohol / a-Ionone, dihydro / Enzymes / Pig liver esterase ... Enzymatic hydrolysis of ( f )-2,4,4-trimethyl-2-cyclohexenyl tate (S)-3. Enantiomerically pure (S)-2 was converted into (R)- acetate [( f )-31 with pig liver esterase yielded (I?)-( +)-2,4,4 -tri- methyl-2-cyclohexen-1-01 [(I?)-21 and unchanged (S)-( -)-ace-