Steroids

Enzymic synthesis of steroid sulfates XVI. Specificity and regulation of human adrenal hydroxysteroid sulfotransferase

JB Adams, D McDonald

Index: Adams, J. B.; McDonald, D. Steroids, 1983 , vol. 41, # 5 p. 575 - 586

Full Text: HTML

Citation Number: 4

Abstract

Abstract Pure hydroxysteroid sulfotransferase (EC 2.8. 2.2) of human adrenal glands possesses a wide substrate specificity towards steroids. This wide specificity has now been found to extend to simple alcohols; normal aliphatic alcohols from C 3 onwards acting as substrates with C 9 showing the highest rate. Increased rate was accompanied by a decrease in Km. In marked contrast to the sulfurylation of steroids such as ...