Aluminum chloride catalyzed Friedel-Crafts reaction of anisole with epoxide accompanying isomerization.

M Inoue, T Sugita, K Ichikawa

Index: Inoue,M. et al. Bulletin of the Chemical Society of Japan, 1978 , vol. 51, p. 174 - 178

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Citation Number: 9

Abstract

The reaction of anisole with propylene oxide by aluminum chloride has been studied in various kinds of solvents. While the normal Friedel-Crafts reaction yielded 2- (methoxyphenyl)-1-propanols, 1, 1-bis (methoxyphenyl)-propanes were also formed in this reaction; these were not obtained by the subsequent reaction of mono (methoxyphenyl) products with another anisole. The yields of 1, 1-bis (methoxyphenyl) propanes increased ...