Self-condensation of. alpha.-oxo esters under Stobbe condensation conditions

RL Augustine, LP Calbo Jr

Index: Augustine,R.L.; Calbo,L.P. Journal of Organic Chemistry, 1968 , vol. 33, p. 838 - 840

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Abstract

Stobbe condensations have been run successfully on p3 and 8-keto esters4 to give the expected products. With &keto esters only products resulting from cleavage of the keto ester were formed. 5 No mention could be found in the literature, however, of the use of a-keto esters or acids in this reaction. In light of the reported successful base-catalyzed mixed aldol condensations between aldehydes and ketones and pyruvic acidl6 phenylpyruvic acid,' ...