Synthesis of chiral cyclophanes based on meta-terphenyl and pyridyl blocks

P Rajakumar, M Srisailas

Index: Rajakumar, Perumal; Srisailas, Muthialu Tetrahedron, 2001 , vol. 57, # 48 p. 9749 - 9754

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Citation Number: 27

Abstract

Extensive studies on the use of chiral binaphthol based crown ethers as hosts for molecular recognition have been carried out as early as 1970. 1 Though the first binaphthyl crown ether was reported in 1973, 2 the m-terphenyl and pyridyl based cyclophanes are not known so far. Cyclophanes based on m-terphenyl building blocks possess a large non-collapsible rigid cavity. 3 Hence, bisbinaphthyl cyclophanes based on m-terphenyls would have a macrocyclic cavity and ...