Advanced Synthesis & Catalysis

Palladium??Catalyzed Asymmetric Hydrogenation of Simple Ketimines Using a Brønsted Acid as Activator

XY Zhou, M Bao, YG Zhou

Index: Zhou, Xiao-Yu; Bao, Ming; Zhou, Yong-Gui Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 84 - 88

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Citation Number: 26

Abstract

The preparation of chiral amines from the transition metal-catalyzed asymmetric hydrogenation or transfer hydrogenation of prochiral imines represents one of the most direct and efficient approaches that open a straightforward route to valuable building blocks for natural products, pharmaceuticals and other fine chemical compounds.1 A variety of chiral metal catalysts has been successfully applied to this reaction over the last few decades. Among the various catalytic systems so ...