Mechanism of 1-phenyl-1, 4-dihydropyridine formation in reaction of 1-phenylpyridinum chloride with alkali metal alkoxides

…, J Krechl, M Bělohradský, P Trška

Index: Kuthan, Josef; Krechl, Jiri; Belohradsky, Martin; Trska, Petr Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 3 p. 597 - 602

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Abstract

Abstract Quaternary salt Ia reacts with sodium and lithium alkoxides to give 1-phenyl-1, 4- dihydropyridine (IIIa) together with unsaturated aldehyde IVa. The reaction mechanism for formation of compound IVa from the primarily arising 2-alkoxy-1-phenyl-1, 2- dihydropyridines is suggested on the basis of products IIIb and IVb, arising from the 3, 4, 5- trideuterio precursor Ib.