Evaluation of the carbonyl metallo immunoassay (CMIA) for the determination of traces of the herbicide atrazine

N Fischer-Durand, A Vessieres, JM Heldt…

Index: Fischer-Durand, Nathalie; Vessieres, Anne; Heldt, Jan-Martin; le Bideau, Franck; Jaouen, Gerard Journal of Organometallic Chemistry, 2003 , vol. 668, # 1-2 p. 59 - 66

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Citation Number: 25

Abstract

The non-isotopic immunoassay (CMIA) was investigated for the quantification of the herbicide atrazine. This assay combines transition metal carbonyl complex and Fourier transform infrared spectroscopy. We describe the synthesis of three dicobalt hexacarbonyl tracers, derivatives of atrazine. Their relative binding affinity towards two purified IgG fractions of polyclonal rabbit anti-sera (anti-atrazine and-simazine) was evaluated by ...