Synlett

A sterically bulky cyclic thiourea as an efficient ligand for palladium-catalyzed aerobic oxidation of alcohols

M Yang, KT Yip, JH Pan, YC Chen, NY Zhu, D Yang

Index: Yang, Min; Yip, Kai-Tai; Pan, Jie-Hui; Chen, Ying-Chun; Zhu, Nian-Yong; Yang, Dan Synlett, 2006 , # 18 p. 3057 - 3060

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Citation Number: 13

Abstract

Abstract Sterically bulky N, N¢-disubstituted cyclic thiourea ligand L1 has been demonstrated as an efficient ligand in palladium-catalyzed oxidation of alcohols using molecular oxygen as an oxidant. This new catalyst system has been applied to a wide variety of substrates such as benzylic alcohols, aliphatic secondary alcohols and allylic alcohols, producing the corresponding carbonyl compounds in good to excellent yields.