Organic letters

Regioselective Synthesis of α, α-Difluorocyclopentanone Derivatives: Domino Nickel-Catalyzed Difluorocyclopropanation/Ring-Expansion Sequence of Silyl Dienol …

T Aono, H Sasagawa, K Fuchibe, J Ichikawa

Index: Fuchibe, Kohei; Koseki, Yuta; Sasagawa, Hisashi; Ichikawa, Junji Chemistry Letters, 2011 , vol. 40, # 10 p. 1189 - 1191

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Citation Number: 3

Abstract

Silyl dienol ethers prepared from α, β-unsaturated ketones underwent nickel-catalyzed difluorocyclopropanation of the electron-rich alkene moiety with trimethylsilyl 2, 2-difluoro-2- (fluorosulfonyl) acetate. The subsequent vinylcyclopropane–cyclopentene rearrangement

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