Studies toward the synthesis of natural and unnatural dienediynes. Part 2: A practical approach to functionalised cyclopentenones

…, S Khan, LM Frost, NJ Smith, S Cheung, G Pairaudeau

Index: Caddick; Khan; Frost; Smith; Cheung; Pairaudeau Tetrahedron, 2000 , vol. 56, # 45 p. 8953 - 8958

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Citation Number: 30

Abstract

Our own work in this area has focused on NCS and Kedarcidin, and in particular we have been interested in designing synthetic approaches to compounds which can find common use in total synthesis and provide functionalised analogues. 5 From our perspective, a particularly attractive and compelling synthetic objective was the identification of a suitable cyclopentane building block which could be readily prepared on large scale. This paper describes in full a study ...