Differential tuning of the electron transfer parameters in 1, 3, 5-triarylpyrazolines: A rational design approach for optimizing the contrast ratio of fluorescent probes

J Cody, S Mandal, L Yang…

Index: Cody, John; Mandal, Subrata; Yang, Liuchun; Fahrni, Christoph J. Journal of the American Chemical Society, 2008 , vol. 130, p. 13023 - 13032

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Citation Number: 57

Abstract

A large class of cation-responsive fluorescent sensors utilizes a donor− spacer− acceptor (D− A) molecular framework that can modulate the fluorescence emission intensity through a fast photoinduced intramolecular electron transfer (PET) process. The emission enhancement upon binding of the analyte defines the contrast ratio of the probe, a key property that is particularly relevant in fluorescence microscopy imaging applications. Due ...