Synthesis and evaluation of 3-acyltetronic acid-containing metal complexing agents

…, M Hémadi, NT Ha-Duong, JMEH Chahine, T Le Gall

Index: Rouleau, Julien; Korovitch, Alexandre; Lion, Claude; Hemadi, Miryana; Ha-Duong, Nguyet-Thanh; El Hage Chahine, Jean-Michel; Le Gall, Thierry Tetrahedron, 2013 , vol. 69, # 51 p. 10842 - 10848

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Citation Number: 5

Abstract

Abstract Potential metal chelators containing one or several acyltetronic acid moieties were prepared from cyclic or acyclic amines and polyamines, and from bis (phenols) by reaction with 1–4 equiv of 3-bromoacetyltetronic acid in the presence of potassium carbonate. The affinity constants of the chelating agents for toxic metallic cations Cd 2+, Cs+, and Pb 2+ and for dimethylarsinic acid were measured, at pH 7.5 and 9.3. Compound 4, an acyclic ...