Russian Journal of Organic Chemistry

Adamantylation of saturated nitrogen-containing heterocycles

GM Butov, VM Mokhov

Index: Butov; Mokhov Russian Journal of Organic Chemistry, 2014 , vol. 50, # 3 p. 447 - 448 Zh. Org. Khim., 2014 , vol. 50, # 3 p. 455 - 456,2

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Citation Number: 5

Abstract

Among biologically active adamantane derivatives, a particular place is occupied by those containing nitrogen heterocycles, including saturated rings with one or two nitrogen atoms and morpholine ring, where the adamantyl radical is attached to the nitrogen atom. Derivatives of 1-and 2-aminoadamantane in which the amino nitrogen atom is a part of heterocyclic fragment attract interest as antiviral and anti-Parkinson drugs [1, 2]. The ...