Microwave-assisted synthesis and antimicrobial screening of new imidazole derivatives bearing 4-thiazolidinone nucleus

NC Desai, VV Joshi, KM Rajpara, HV Vaghani…

Index: Desai; Joshi; Rajpara; Vaghani; Satodiya Medicinal Chemistry Research, 2013 , vol. 22, # 4 p. 1893 - 1908

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Citation Number: 15

Abstract

Abstract A new series of compounds 2-((1-(4-(4-arylidene-2-methyl-5-oxo-4, 5-dihydro-1 H- imidazol-1-yl) phenyl) ethylidene) hydrazono) thiazolidin-4-ones (4a–o) have been synthesized under conventional and microwave irradiation method. All compounds were characterized by IR, 1 H NMR, 13 C NMR and mass spectra. Newly synthesized compounds were screened for their antibacterial and antifungal activities on Escherichia coli, ...