Tetrahedron letters

Chloromethylaluminum 2 (2-propenyl) anilide-a convenient reagent for the conversion of lactones into protected hydroxy acids

AGM Barrett, D Dhanak

Index: Barrett, Anthony G.M.; Dhanak, Dashyant Tetrahedron Letters, 1987 , vol. 28, # 29 p. 3327 - 3330

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Citation Number: 11

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The title reagent reacts with γ and δ lactones to provide hydroxy amides which can be easily converted into protected N-acyl indoles. Mild saponification provides indole and the protected hydroxy acid. ... Generalized strategy for converting γ and δ lactones into differentiallly ...

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