An efficient synthesis of brominated 4-alkyl-2 (5H)-furanones

G Iskander, R Zhang, DSH Chan, DSC Black…

Index: Iskander, George; Zhang, Ruonan; Chan, Daniel Shiu-Hin; Black, David StC; Alamgir, Mahiuddin; Kumar, Naresh Tetrahedron Letters, 2009 , vol. 50, # 32 p. 4613 - 4615

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Citation Number: 22

Abstract

A versatile method for the synthesis of novel brominated 4-alkyl-2 (5H)-furanones under mild reaction conditions is described. This synthetic strategy requires only one chromatographic separation over six steps and employs the cyclodehydration of brominated levulinic acid as the key transformation.

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