European journal of organic chemistry

Substituent Effects in Tandem Ring??Closing Metathesis Reactions of Dienynes

FD Boyer, I Hanna

Index: Boyer, Francois-Didier; Hanna, Issam European Journal of Organic Chemistry, 2006 , # 2 p. 471 - 482

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Citation Number: 18

Abstract

Abstract Several dienynes bearing different substituents have been synthesized and subjected to a ring-closing metathesis (RCM) reaction using ruthenium carbene complexes. Dienynes containing a pre-existing ring and a quaternary center attached to the alkyne give the expected tandem metathesis products in high yields. For these substrates, a high selectivity for different ring sizes was achieved by modifying the reactivity of one alkene. In ...