Journal of the American Chemical Society

Di-(α-and β-Substituted Aminoethyl)-benzenes. I. 2, 5-bis-(2-Aminoethyl)-hydroquinones

JH Wood, RE Gibson

Index: Wood; Gibson Journal of the American Chemical Society, 1949 , vol. 71, p. 393

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Citation Number: 43

Abstract

Pressor, bronchodilator and antihistamine activity tests, made by The Lilly Research Laboratories of Eli Lilly and Company on the hydrochloride salts of I and its 0-methyl, N- dimethyl and 0-methyl-N-dimethyl derivatives, revealed that these amines are inactive in these respects. They showed less than 10%“Egotrate” activity. Since the introduction of a second@-aminoethyl function does not significantly alter the chemical properties of the ...