Synthesis of some 3, 4-disubstituted-6, 7-dihydro-imidazo [2, 1-b][1, 3] thiazole and 3, 4-disubstituted-7, 8-dihydro-6H-imidazo [2, 1-b][1, 3] thiazine derivatives and …

A Meriç, Z Incesu, İ Hatipoğlu

Index: Meric, Asiye; Incesu, Zerrin; Hatipoglu, Ibrahim Medicinal Chemistry Research, 2008 , vol. 17, # 1 p. 30 - 41

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Citation Number: 14

Abstract

Abstract This article describes the synthesis of 3, 4-disubstituted-6, 7-dihydro-imidazo [2, 1- b][1, 3] thiazoles and 3, 4-disubstituted-7, 8-dihydro-6H-imidazo [2, 1-b][1, 3] thiazines, having substituted or nonsubstituted phenyl rings at the 5, 6 and 2, 3 positions, respectively, their cytotoxic effects through noncancer (F2408) and cancer (5RP7) cells, and their detailed 1 H-and 13 C-nuclear magnetic resonance (NMR) spectral characterization. The title ...