Russian journal of organic chemistry

New synthesis of diphenylmethanamines

EV Aver'yanova, VP Sevodin

Index: Aver'yanova; Sevodin Russian Journal of Organic Chemistry, 2006 , vol. 42, # 9 p. 1417 - 1419

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Citation Number: 1

Abstract

Diphenylmethyl derivatives of ethers and amines constitute structural fragments of drugs with a broad spectrum of activity, in particular antihistaminic drugs, mild tranquilizers, etc. [1]; diarylmethylidene fragment is a structural base of 1,4 benzodiazepine tranquilizers [2]. Bell et al. [3, 4] showed that o aminophenyl (phenyl)methaneamines can be synthesized by reduc tion of diarylmethylidenamines obtained from o amino benzophenones. N,N Dialkyl(o aminophenyl)phenyl ...