A new preparative route to α-fluoroacrylic acid

…, S Paganelli, B Vicentini, C Zarantonello

Index: Botteghi; Paganelli; Vicentini; Zarantonello Journal of Fluorine Chemistry, 2001 , vol. 107, # 1 p. 113 - 116

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Citation Number: 6

Abstract

Rhodium-catalyzed hydroformylation of vinyl fluoride (VF) followed by careful oxidation of the regiospecifically produced 2-fluoropropanal afforded 2-fluoropropanoic acid (2) in about 70% yield. Dehydrogenation of 2 to α-fluoroacrylic acid (1) was accomplished by a chlorination-dehydrochlorination reaction in more than 60% yield.