Benzofuran dioxetanes, a new class of mutagenic agents: synthesis by photooxygenation of benzofuran derivatives

…, O Albrecht, E Feineis, I Reuther…

Index: Adam, Waldemar; Albrecht, Olaf; Feineis, Erich; Reuther, Irene; Saha-Moeller, Chantu R.; et al. Liebigs Annalen der Chemie, 1991 , p. 33 - 40

Full Text: HTML

Citation Number: 5

Abstract

Abstract Tetraphenylporphine-sensitized photooxygenation of benzofuran derivatives 1 afforded the corresponding benzofuran dioxetanes 2 in good yields. Allylic hydroperoxides 3 were formed regioselectively from 2, 3-dimethyl-substituted benzofurans as minor products, except in the case of the benzofuran 1d, which gave predominantly the hydroperoxide 3d. The relative reactivities of the benzofurans toward singlet oxygen depended on the nature ...