The Journal of Organic Chemistry

Radical-Mediated Synthesis of Bridgehead-Substituted Bicycloalkanes. A Convenient Route to the Bicyclo [3.2. 1] octyl System

EW Della, AM Knill

Index: Della; Knill Journal of Organic Chemistry, 1995 , vol. 60, # 11 p. 3518 - 3522

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Citation Number: 8

Abstract

Cyclization of the (3-methylenecyclohexy1) ethyl radical (9) to the isomeric l-bicyclo [3.2. 1loctylmethyl radical (10) occurs with an activation energy of 11.6 kcal mol-', a barrier which compares favorably with the calculated value of 12.6 kcal mol-l determined by force field