Ratiometric fluorescence sensing and cellular imaging of Cu 2+ by a new water soluble trehalose-naphthalimide based chemosensor

…, C Sgarlata, M Sgarzi, G Tomaselli, G Arena, L Prodi

Index: Grasso, Giuseppa Ida; Gentile, Salvatore; Giuffrida, Maria Laura; Satriano, Cristina; Sgarlata, Carmelo; Sgarzi, Massimo; Tomaselli, Gaetano; Arena, Giuseppe; Prodi, Luca RSC Advances, 2013 , vol. 3, # 46 p. 24288 - 24297

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Citation Number: 14

Abstract

A new turn-on Cu2+ fluorescent sensor (CST) having a trehalose moiety, which confers a relatively large solubility in water, has been synthesized. The chemosensor is therefore suitable for studies in aqueous solution. Full potentiometric and UV-vis characterization evidence that at physiological pH CST forms with Cu2+ a species with a 1: 1 stoichiometry allowing for a straightforward correlation between CST response and copper (II) ...