Chemical Communications

Palladium (II)-gated ion channels

CP Wilson, SJ Webb

Index: Wilson, Craig P.; Webb, Simon J. Chemical Communications, 2008 , # 34 p. 4007 - 4009

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Citation Number: 19

Abstract

Taking inspiration from the work of Kobuke et al. 11 and Regen et al., 12 we used cholic acid as the basis of our ligand-gated channels (Fig. 2). Kobuke and co-workers created covalently-linked head-to-head dimers of cholic acid that spanned phospholipid bilayers and self-assembled to form hydroxyl-lined membrane channels. These compounds gave good rates of alkali metalion transport, showing selectivity for the transport of K + over Na + by up to ...