Tetrahedron letters

Direct synthesis of hetero-biaryl compounds containing an unprotected NH 2 group via Suzuki–Miyaura reaction

T Itoh, T Mase

Index: Itoh, Takahiro; Mase, Toshiaki Tetrahedron Letters, 2005 , vol. 46, # 20 p. 3573 - 3577

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Citation Number: 96

Abstract

Hetero-biaryl compounds were prepared via the Suzuki–Miyaura coupling reaction of hetero- aryl moieties containing an unprotected NH2 group and arylboronic acids. Dt-BPF was found to be an efficient ligand for the cross-coupling of NH2-unprotected hetero-aryl chlorides with phenylboronic acid.