Synthesis and interconversion of the four isomeric 6-oxo-2, 4-heptadienoic acids

AL Feliu, S Seltzer

Index: Feliu, Anthony L.; Seltzer, Stanley Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 447 - 451

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Citation Number: 12

Abstract

The synthesis of the structural isomers of 6-oxo-2, 4-heptadienoic acid was undertaken as a means of providing analogues to investigate the structural requirements of maleylacetone cis-trans isomerase. 6-0xo-2 (Z), 4 (E)-heptadienoic acid and the methyl esters of 6-oxo-2 (E), 4 (Z)-,~-oxo-~(Z),~(Z)-, and 6-oxo-2 (E), 4 (E)-heptadienoic acid were synthesized. Base- catalyzed hyrolysis of these esters furnished the corresponding acids except in the case of ...