Microwave-assisted selective protection of glutaraldehyde and its symmetrical derivatives as monoacetals and-thioacetals

H Flink, T Putkonen, A Sipos, R Jokela

Index: Flink, Heli; Putkonen, Tiina; Sipos, Attila; Jokela, Reija Tetrahedron, 2010 , vol. 66, # 4 p. 887 - 890

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Citation Number: 8

Abstract

Six monoprotected acetals and-thioacetals of glutaradehyde and its symmetrical dimethyl derivatives were synthesized. Microwave-assisted heating proved to be a substantially more selective method for monoprotection than conventional heating. All reactions were efficient and only traces of diprotected material were formed.