The Journal of organic chemistry

Regioselective Sonogashira couplings of 2, 4-dibromoquinolines. A correction

JM Nolan, DL Comins

Index: Nolan, Jason M.; Comins, Daniel L. Journal of Organic Chemistry, 2003 , vol. 68, # 9 p. 3736 - 3738

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Citation Number: 30

Abstract

Heteronuclear multiple bond correlation (HMBC) was used to determine the regiochemical outcome of palladium-catalyzed carbon-carbon bond formation between 2, 4- dibromoquinolines and terminal acetylenes. The observed regioselectivity of these coupling reactions is opposite to that reported in the literature for analogous reactions.