Synthesis and antimicrobial activity of 2-(4-formyl-3-pyrazolyl)-3-phenylindoles

…, VS Gokak, LD Basanagoudar

Index: Maddirala, Shambabu Joseph; Gokak, Vidya S.; Basanagoudar, Linganagouda D. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 11 p. 2410 - 2415

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Abstract

Abstract: Vilsmeier-Haack reagent (POCl 3-DMF) on reaction with hydrazones 3a-i derived from 2-acetyl-3-phenylindoles 2a-c furnishes 2-(4-formyl-3-pyrazolyl)-3-phenylindoles 4a-i. The structures of these compounds have been established on the basis of their elemental analyses and spectral (IR, 1 H NMR) data. All the pyrazole derivatives 4a-i and their azines 5a-i have been tested for their antimicrobial and antifungal activities.