4-substituted cubylcarbinylamines: a new class of mechanism-based monoamine oxidase B inactivators

JJP Zhou, J Li, S Upadhyaya, PE Eaton…

Index: Eaton; Nodari; Tsanaktsidis; Upadhyaya Synthesis, 1995 , # 5 p. 501 - 502

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Citation Number: 19

Abstract

Cubylcarbinylamine (1a),(4-cyclopropylcubyl) carbinylamine (1b), and (4-phenylcubyl) carbinylamine (1c) were synthesized and shown to be time-dependent, irreversible inactivators of monoamine oxidase B (MAO B). Substrate protects the enzyme from

Antiulcer Agents. III. Synthesis and Antiulcer Activity of N-(3-(3-Piperidinomethylphenoxy) propyl) pentacyclo (4.2. 0.02, 5.03, 8.04, 7) octane Carboxamides and …

[Hasegawa; Nigo; Kakita; Toyoda; Toya; Ueda Chemical and Pharmaceutical Bulletin, 1993 , vol. 41, # 10 p. 1760 - 1768]

Effective synthetic routes to cubylcarbinol derivatives

[Priefer, Ronny; Farrell, Patrick G.; Harpp, David N. Synthesis, 2002 , # 18 p. 2671 - 2673]

Proton magnetic resonance spectra of cubane derivatives. I. Syntheses and spectra of mono-and 1, 4-disubstituted cubanes

[Edward,J.T. et al. Journal of the American Chemical Society, 1976 , vol. 98, # 11 p. 3075 - 3085]