Tetrahedron Letters

Novel and efficient protocol for the syntheses of N-1 substituted thiohydantoin and a bicyclothiohydantoin under solvent-free conditions

V Kumar, H Rana, R Sankolli, MP Kaushik

Index: Kumar, Vinod; Rana, Hemlata; Sankolli, Ravish; Kaushik Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2377 - 2379

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Citation Number: 4

Abstract

A novel approach for the synthesis of N-1 substituted thiohydantoin has been developed to give quantitative yields of the desired products. The efficient synthesis of bis-thiohydantoin derivative and bicyclothiohydantoin has extended scope and applicability of present method. Solvent-free conditions and very easy work-up procedure make the reaction convenient and eco-friendly. All the products were characterized by spectroscopic ...