Synthesis and biological activities of some novel 2-amino-(5 or 7-substituted-2-oxoindolin-3-ylidene) benzoxazole-5-carbohydrazide derivatives

…, A Rama Narsimha Reddy…

Index: Rajyalakshmi; Reddy, A. Rama Narsimha; Sarangapani Letters in Drug Design and Discovery, 2012 , vol. 9, # 6 p. 625 - 632

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Citation Number: 3

Abstract

A series of 2-amino-(5 or 7-substituted-2-oxoindolin-3-ylidene) benzoxazole-5- carbohydrazide derivatives were synthesized by treating 2-aminobenzoxazole-5- carbohydrazide with different substituted isatins. All the synthesized derivatives (VI al) were screened for their in vitro anticancer (against HeLa, IMR-32 & MCF-7 cancer cell lines), antioxidant (against DPPH radicals) and antimicrobial activities. The results of these ...