Tetrahedron

A study on the synthesis of structural analogs of bis-indole alkaloid caulerpin: a step-by-step synthesis of a cyclic indole-tetramer

O Talaz, N Saracoglu

Index: Talaz, Oktay; Saracoglu, Nurullah Tetrahedron, 2010 , vol. 66, # 10 p. 1902 - 1910

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Citation Number: 13

Abstract

The syntheses of structural isomers of bis-indole alkaloid caulerpin are investigated. Construction of the caulerpin skeleton is based on the Fisher indolization reaction of the appropriate cyclooctane-diones or cyclooctanone. In addition, a step-by-step synthesis of one isomer from possible four cyclic indole-tetramers has first been described.