Tetrahedron

The amine exchange/biaryl coupling sequence: a direct entry to the phenanthro [9, 10-d] heterocyclic framework

R Olivera, R SanMartin, I Tellitu, E Domı́nguez

Index: Olivera, Roberto; SanMartin, Raul; Tellitu, Imanol; Dominguez, Esther Tetrahedron, 2002 , vol. 58, # 15 p. 3021 - 3037

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Citation Number: 26

Abstract

Novel phenanthro [9, 10-d] pyrimidines and phenanthro [9, 10-d][1, 2] oxazoles are regioselectively prepared by the application of a straightforward synthetic pathway, starting from new o, o′-dihalogenated and non-halogenated 4, 5-diarylpyrimidines and 4, 5- diarylisoxazoles, respectively, prepared via a tandem amine exchange/heterocyclization of diarylenaminones. A comparative study of biaryl coupling methodologies provides two ...