Regio??and Enantioselective Catalytic Hydrophosphorylation of Vinylarenes

…, G Francio, IP Beletskaya, W Leitner

Index: Shulyupin, Mstislav O.; Francio, Giancarlo; Beletskaya, Irina P.; Leitner, Walter Advanced Synthesis and Catalysis, 2005 , vol. 347, # 5 p. 667 - 672

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Citation Number: 31

Abstract

Abstract Regioselective and stereoselective hydrophosphorylation of vinylarenes 1 with pinacol H-phosphonate 2 can be achieved with transition metal catalysts. The use of rhodium catalysts such as the Wilkinson complex leads to the anti-Markovnikov adducts 3 as the only observable reaction products. In contrast, palladium catalysts give high selectivities for the Markovnikov adducts 4. In the presence of (R, S)-BINAPHOS as a chiral ligand, ...