The Journal of Organic Chemistry

Dimetalation of N-tert-butylmethacrylamide: a new synthetic reagent

JJ Fitt, HW Gschwend

Index: Fitt, John J.; Gschwend, Heinz W. Journal of Organic Chemistry, 1980 , vol. 45, # 21 p. 4257 - 4259

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Citation Number: 18

Abstract

(9) Available in a manner similar to that reportedZ for the five-mem- bered lactones. The details will be published in the full account of this work. (10) The known aldehyde ii was prepared by reported methods: Oh- rui, H.; Emoti, S. Tetrahedron Lett. 1975, 2765. This aldehyde was converted to 11 by a Wittig reaction (Ph$'+CH2CHJ3r-, KOC,H,-t, THF, -78 OC to room temperature), hydrolysis to the lactol (KOH, CH30H, room temperature), and Moffatt oxidation (ClCOCOCl, Me2S0, ...

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