Analyzing Site Selectivity in Rh2 (esp) 2-Catalyzed Intermolecular C–H Amination Reactions

…, MS Oderinde, JL Roizen, J Du Bois…

Index: Bess, Elizabeth N.; Deluca, Ryan J.; Tindall, Daniel J.; Oderinde, Martins S.; Roizen, Jennifer L.; Du Bois; Sigman, Matthew S. Journal of the American Chemical Society, 2014 , vol. 136, # 15 p. 5783 - 5789

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Citation Number: 30

Abstract

Predicting site selectivity in C–H bond oxidation reactions involving heteroatom transfer is challenged by the small energetic differences between disparate bond types and the subtle interplay of steric and electronic effects that influence reactivity. Herein, the factors governing selective Rh2 (esp) 2-catalyzed C–H amination of isoamylbenzene derivatives are investigated, where modification to both the nitrogen source, a sulfamate ester, and ...