Oxo-tethered ruthenium (II) complex as a bifunctional catalyst for asymmetric transfer hydrogenation and H2 hydrogenation

…, N Sayo, T Saito, Y Kayaki, T Ikariya

Index: Ito, Masato; Ootsuka, Takashi; Watari, Ryo; Shiibashi, Akira; Himizu, Akio; Ikariya, Takao Journal of the American Chemical Society, 2011 ,  vol. 133,  # 12  p. 4240 - 4242

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Citation Number: 134

Abstract

Newly developed oxo-tethered Ru amido complexes (R, R)-1 and their HCl adducts (R, R)-2 exhibited excellent catalytic performance for both asymmetric transfer hydrogenation and the hydrogenation of ketonic substrates under neutral conditions without any cocatalysts to give chiral secondary alcohols with high levels of enantioselectivity.