New route to. gamma.-ketoaldehydes. Application to the synthesis of cis-jasmone
K Oshima, H Yamamoto, H Nozaki
Index: Oshima,K. et al. Journal of the American Chemical Society, 1973 , vol. 95, p. 4446 - 4447
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Citation Number: 75
Abstract
The efficiency and generality of the reaction coupled with the ready availability of the starting materials render it very useful in the preparation of heterocycles containing the-N= CHQ- unit. A typical experimental procedure is illustrated by the reaction of yaminopropanol with tert-butyl isocyanide in the presence of silver cyanide leading to the formation of 5, 6-dihydro- 4H-1, 3-oxazine. A mixture of 1.5 g (20 mmol) of y-aminopropanol, 1.7 g (20 mmol) of ...
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