Facile Synthesis of Second-Generation Dendrons with an Orthogonal Functional Group at the Focal Point
RK Cheedarala, V Sunkara, JW Park
Index: Cheedarala, Ravi Kumar; Sunkara, Vijaya; Park, Joon Won Synthetic Communications, 2009 , vol. 39, # 11 p. 1966 - 1980
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Citation Number: 3
Abstract
Abstract Facile synthesis of second-generation dendrons with an aldehyde, epoxy, or t-Boc group at the focal point and nine carboxylic acid groups at the periphery is reported. The scheme includes a coupling of the first-generation dendrons and a two-step, one-pot reaction that proceeds through a Boc deprotection and in situ conjugation at the focal point.
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