Na+-Glucose Cotransporter Inhibitors as Antidiabetic Agents. II. Synthesis and Structure-Activity Relationships of 4'-Dehydroxyphlorizin Derivatives.

M Hongu, T Tanaka, N Funami, K SAITO…

Index: Chemical and Pharmaceutical Bulletin, , vol. 46, # 1 p. 22 - 33

Full Text: HTML

Citation Number: 41

Abstract

... Chemistry In order to investigate SARs, we first synthesized 4'- dehydroxyphlorizin derivatives 2—34 having various sub ... (6) 1998 Pharmaceutical Society of ... of compound 72 in CHZCIZ: Table 2. Physical and Biological Properties of 4'~Dehydroxyphlorizin Derivatives (2) Vol. ...