New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine

P Angehrn, S Buchmann, C Funk…

Index: Auterhoff; Oettmeier Archiv der Pharmazie, 1975 , vol. 308, # 10 p. 732 - 736

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Citation Number: 57

Abstract

... Volume: Page ... Nalidixic acid, 9 the progenitor of the quinolones, as well as the coumarin antibiotics, 10 had been discovered by the traditional search ... According to the retrosynthetic analysis of 1, a classical lactonization of ω-hydroxy acid II (P = H) is used for the ...

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