First iron-catalyzed synthesis of oximes from styrenes

…, R Jackstell, N Vogl, C Weckbecker, M Beller

Index: Prateeptongkum, Saisuree; Jovel, Irina; Jackstell, Ralf; Vogl, Nadine; Weckbecker, Christoph; Beller, Matthias Chemical Communications, 2009 , # 15 p. 1990 - 1992

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Citation Number: 8

Abstract

For our initial experiments, the reaction of styrene with tert. butyl nitrite in the presence of iron phthalocyanine complex (Fe(Pc)) was chosen as a model. Selected results of the optimization of reaction conditions are summarized in Table 1. First tests showed only low conversion of the olefin. However, a survey of solvents indicated that high activity is observed in EtOH using NaBH 4 as reductant. Notably, higher catalyst concentration as well as prolonged reaction time ...