Large-scale asymmetric synthesis of novel sterically constrained 2′, 6′-dimethyl-and α, 2′, 6′-trimethyltyrosine and-phenylalanine derivatives via alkylation of …

VA Soloshonok, X Tang, VJ Hruby

Index: Tetrahedron, , vol. 57, # 30 p. 6375 - 6382

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Citation Number: 60

Abstract

... Tetrahedron. Volume 57, Issue 30, 23 July 2001, Pages 6375–6382. ... of 8:1, while work-up, after the reaction was allowed to stand at room temperature for 4 h following disappearance of starting material, afforded a mixture (S,α-S)-9a and (S,α-R)-10a with up to 94% de (30:1 ratio ...