Tetracyclic spirooxindole blockers of hNaV1. 7: activity in vitro and in CFA-induced inflammatory pain model

…, S Liu, JA Cadieux, T Hsieh, M Chafeev, S Sun…

Index: Chowdhury, Sultan; Liu, Shifeng; Cadieux, Jay A.; Hsieh, Tom; Chafeev, Mikhail; Sun, Shaoyi; Jia, Qi; Sun, Jianyu; Wood, Mark; Langille, Jonathan; Sviridov, Serguei; Fu, Jianmin; Zhang, Zaihui; Chui, Ray; Wang, Audrey; Cheng, Xing; Zhong, Jing; Hossain, Sazzad; Khakh, Kuldip; Rajlic, Ivana; Verschoof, Henry; Kwan, Rainbow; Young, Wendy Medicinal Chemistry Research, 2013 , vol. 22, # 4 p. 1825 - 1836

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Citation Number: 9

Abstract

... First online: 12 August 2012. Tetracyclic spirooxindole blockers of hNa V 1.7: activity in vitro and in CFA-induced inflammatory pain model. Sultan ChowdhuryAffiliated withDepartment of Medicinal Chemistry, Xenon Pharmaceuticals Inc. Email author; , Shifeng LiuAffiliated withDepartment of Medicinal Chemistry, Xenon Pharmaceuticals Inc. , Jay A. CadieuxAffiliated withDepartment of Medicinal Chemistry, Xenon Pharmaceuticals Inc. ...

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