Synthesis of 4-azahomoadamant-4-ene N-oxides and their 1, 3-dipolar cycloaddition reactivity 1

Y Yu, M Ohno, S Eguchi

Index: Yu, Yang; Ohno, Masatomi; Eguchi, Shoji Tetrahedron Letters, 1991 , vol. 32, # 37 p. 4965 - 4968

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Citation Number: 7

Abstract

Abstract Nitrones incorporated in a homoadamantane ring system, which were obtained by SeO 2-H 2 O 2 oxidation of 4-azahomoadamantane, underwent 1, 3-dipolar cycloaddition reaction with electron-deficient alkynes (not with alkenes) to give 4-substituted isoxazoline specifically by steric reasons.