Design and synthesis of novel heterobiaryl amides as metabotropic glutamate receptor subtype 5 antagonists

SS Kulkarni, AH Newman

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 7 p. 2074 - 2079

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Citation Number: 21

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Medicinal Chemistry Section, National Institute ... The formation of an intermolecular H-bond was confirmed by a downfield shift in the chemical shift of amide N–H proton to δ 9.74 ppm in compound 6b from δ 8.22 ppm for compound 6a. ...